Product Info Summary
SKU: | A00896 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | IF, ICC, WB |
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Product info
Product Name
Anti-Protein lin-28 homolog B LIN28B Antibody
SKU/Catalog Number
A00896
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Protein lin-28 homolog B LIN28B Antibody catalog # A00896. Tested in WB,ICC/IF applications. This antibody reacts with Human,Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Protein lin-28 homolog B LIN28B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00896)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from internal of human CALR.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A00896 is reactive to Lin28b in Human, Mouse
Applications
A00896 is guaranteed for IF, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
26.903kDa
Background of LIN-28B
Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis By similarity.
McCauliffe D.P., J. Clin. Invest. 85:1379-1391(1990).
Rokeach L.A., J. Immunol. 147:3031-3039(1991).
McCauliffe D.P., J. Biol. Chem. 267:2557-2562(1992).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
ICC/IF: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-Protein lin-28 homolog B LIN28B Antibody A00896
Western blot analysis of extracts of mouse liverProtein Target Info & Infographic
Gene/Protein Information For Lin28b (Source: Uniprot.org, NCBI)
Gene Name
Lin28b
Full Name
Protein lin-28 homolog B
Weight
26.903kDa
Superfamily
lin-28 family
Alternative Names
CSDD2; CSDD2protein lin-28 homolog B; FLJ16517; lin-28 homolog B (C. elegans); Lin-28.2; LIN28B; LIN-28B Lin28b|2810403D23Rik, D030047M17Rik, Lin-28.2|lin-28 homolog B (C. elegans)|protein lin-28 homolog B|lin-28B
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Lin28b, check out the Lin28b Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Lin28b: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Protein lin-28 homolog B LIN28B Antibody (A00896)
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No publications found for A00896
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